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Figure 4 | BMC Systems Biology

Figure 4

From: A circuit model of the temporal pattern generator of Caenorhabditis egg-laying behavior

Figure 4

VC inhibits HSN for short periods. A) In lin-39 worms, where VC neurons are genetically ablated, the Ca2+ level in HSN neurons alternates between oscillating and being silent, with all the short silent periods observed in wild-type HSN activity (less than several minutes in magnitude) having disappeared (three representative traces are shown). B) Histogram of wild-type egg-laying events, wild-type HSN spikes and lin-39 HSN spikes. It can be seen that without VC cells, HSN spike intervals longer than one minute are dramatically decreased.

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