Shrunken methodology to genome-wide SNPs selection and construction of SNPs networks

BMC Systems Biology

Table 5 Groups of genes formed for different threshold values.

GOSemSim thresholds	Number of Pairs of Genes	Number of Group of Genes	Number of SNPs Networks
0.18	499	1	10
0.19	448	3	9
0.20	137	9	6
0.21	114	9	6
0.22	111	10	6
0.23	106	10	6
0.24	100	10	6
0.25	78	12	6
0.26	70	10	5
0.27	46	10	2
0.28	27	10	2
0.29	26	9	2
0.30	22	8	2
0.31	22	8	2
0.32	22	8	2
0.33	22	8	2
0.34	17	8	2
0.35	13	7	1

Illustration of number of gene groups and number of gene pairs involved when using different GOSemSim thresholds. The first column is the GOSemSim thresholds from 0.18-0.35. The second column indicates the number of gene pairs involved in the gene network, i.e. the number of gene pairs whose similarity value is bigger than the GOSemSim threshold. The third column is the number of gene groups in the gene network when adopt a particular threshold. The last column indicates the number of SNPs networks constructing from the corresponding gene network under a P <0.01 significance.

ISSN: 1752-0509