Figure 3

Estimated parameter values for Model 1 The parameter sets are estimated by using the genetic algorithm (GA) (A) and the particle swarm optimization (PSO) (B), and in each figure, the histograms of parameter sets with and without DE constraints (right and left sides, respectively) are shown. The bin of the histogram indicates the fraction of the number of parameters within a range (0.01 for k _p and 0.1 for k _m ) to the total number of trial successes (200 in GA and PSO without DE constraints, and 51 and 11 in GA and PSO with DE constraints, respectively) (see details in Methods).