Figure 2

Comparison of our model (solid lines) with the data of the dynamic shift chemostat experiments (dots). Figure 2(a) shows results for the 'forward' dynamic shift experiment. The two repetitions of this 'forward' dynamic shift experiment are shown in Figure 2(b) and Figure 2(c). The cells produce mainly acetate and butyrate when grown at a pH value of 5.7. During the transition phase C. acetobutylicum switches its metabolism (as a function of the external pH) towards the generation of the solvents acetone and butanol at a pH of 4.5. Ethanol is produced during acidogenesis and solventogenesis at approximately the same levels. In Figure 2(d) we demonstrate the comparison of the model and the data for the 'reverse' dynamic shift experiment.