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Table 1 Reactions that form the metabolic pathways of acidogenesis and solventogenesis and the enzymes which are required to catalyze the solvent-associated reactions, i.e. 3-7 and 9.

From: A systems biology approach to investigate the effect of pH-induced gene regulation on solvent production by Clostridium acetobutylicum in continuous culture

Reaction number Reaction Associated enzyme(s)
1 glucose → acetyl-CoA  
2 acetyl-CoA → acetate  
3 acetate + acetoacetyl-CoA → acetoacetate + acetyl-CoA CtfA/B
4 acetyl-CoA → acetoacetyl-CoA ThlA
5 acetyl-CoA → ethanol AdhE
6 butyrate + acetoacetyl-CoA → acetoacetate + butyryl-CoA CtfA/B
7 acetoacetate → acetone Adc
8 butyryl-CoA → butyrate  
9 butyryl-CoA → butanol AdhE, BdhA/B
10 acetoacetyl-CoA → butyryl-CoA