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Table 2 Summary of results for variations on the basic model

From: The coupling of pathways and processes through shared components

Scenario Result
An additional component is involved the uptake of X by one of the two pathways through a complex formation mechanism. The additional component can control how signalling through X is divided between the two pathways. This may enhance signalling specificity. The degree of control the additional component has depends on the mechanism of complex formation.
The shared component is involved in two downstream pathways which display switching behaviour. Where uptake of the shared component is significant, the switching behaviour of one pathway may influence that of the other. This can result in either a specific ordering of activation, or coordinated activation, of the two pathways.
One of the downstream components, and its complex with the shared component, is diffusible. The shared component is spread across the domain. This results in uptake being significant across the domain, with the spatial distribution of the nondiffusible components also affected.
  1. A summary of results for the biologically motivated variations on the basic model is presented. These demonstrate how the effects considered may play a role in diverse biological contexts.