GSEA of the hORGNet and its two modules (hStemModule and hDiffModule) using transcriptome data during human organogenesis. (A) Human embryos from Carnegie stages 9 (S9) to 14 (S14). (B) Human embryos during weeks (wk) 4-9. The normalized enrichment score (NES) reflects the degree to which the hORGNet (in red), the hStemModule (in green) and the hDiffModule (in blue) are overrepresented at the top (reflected by a positive NES) or bottom (indicated by a negative NES) of a ranked gene list predefined by expression data from each stage. Statistically significant NES enrichments (i.e., FDR < 0.05) of NES are highlighted with bold and italic text.