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Table 2 Comparison of the areas with respect to different time ranges in Figure 9

From: An Integrated Mathematical Model of Thrombin-, Histamine-and VEGF-Mediated Signalling in Endothelial Permeability

MLC activation curve Area under MLC activation curve with respect to different time range (time unit:min)
  0-10 10-20 20-30 30-40 40-50 50-60 60-70 70-80
Curve 1:Thrombin + VEGF induced activation 5.0 6.2 6.7 5.1 3.4 2.4 1.9 1.4
Curve 2:VEGF-mediated activation 4.1 3.5 2.9 3.2 3.3 3.4 3.4 3.1
Curve 3:Thrombin-mediated activation 4.0 2.6 2.0 1.1 0.05 0.5 0.4 0.3
Simple sum of curve 2 and 3 8.1 6.1 4.9 4.3 3.35 3.9 3.8 3.4
Area difference between curve 1 and simple sum of curve 2 and 3 -3.1 0.1 1.8 0.7 0.05 -1.5 -1.9 -2.0
  1. Comparison of the areas under the thrombin and VEGF induced MLC activation curve with those of thrombin-induced and VEGF-induced MLC activation curves with respect to different time ranges in Figure 9.