Figure 5From: Distinct configurations of protein complexes and biochemical pathways revealed by epistatic interaction network motifsExamples of NPP and NNP motifs in typical cellular contexts. A) NPP motif where the 'positive' node, URE2, regulates GLN3 and GAT1 in the yeast nitrogen catabolite repression (NCR) pathway. B) A network made up of NNP motifs shows how the 'P' edge often separates two members of a protein complex, while the 'N' edges form a link to a different protein complex.Back to article page