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Table 6 Results (CPU time in seconds) of the optimization of case O1-v4 for specific regions of k2 and k5 obtained with the customized OA for the rGMA model.

From: Steady-state global optimization of metabolic non-linear dynamic models through recasting into power-law canonical models

k5/k2

1

2

3

4

5

6

7

8

8

0.13

0.27

0.23

0.18

0.17

0.19

0.28

0.28

7

0.26

0.28

0.28

0.26

0.28

0.23

0.32

0.25

6

0.32

0.30

0.28

0.28

0.27

0.23

0.19

0.25

5

0.31

0.21

0.25

0.25

0.26

0.28

0.27

0.29

4

0.25

0.27

0.32

0.30

0.25

0.27

0.26

0.28

3

0.20

0.22

0.28

0.28

0.29

0.30

0.19

0.53

2

0.28

0.25

0.19

0.19

0.22

0.17

0.30

0.25

1

0.23

0.24

0.26

0.27

0.23

0.21

0.24

0.31

  1. Domain of each kr(4 ≤ k2 ≤ 5;0.2 ≤ k5 ≤ 0.8) has been split into 8 intervals with equal width.