Table 1 Enriched GO terms among the toxicity-modulating genes
GO IDDescription | P-value | Adjusted P-value | x/X* (%) | n/N** (%) | |
|---|---|---|---|---|---|
6974 | response to DNA damage stimulus | 6.8E-19 | 2.1E-16 | 15.3 | 4.8 |
6259 | DNA metabolic process | 3.0E-16 | 4.7E-14 | 19.0 | 7.6 |
6281 | DNA repair | 2.9E-16 | 4.7E-14 | 12.8 | 3.9 |
22402 | cell cycle process | 6.6E-12 | 5.4E-10 | 17.4 | 7.9 |
6394 | RNA processing | 2.5E-09 | 1.5E-07 | 16.0 | 7.9 |
7001 | chromosome organization and biogenesis | 4.4E-09 | 2.4E-07 | 14.4 | 6.8 |
6365 | rRNA processing | 1.3E-08 | 6.4E-07 | 9.2 | 3.5 |
6260 | DNA replication | 1.4E-08 | 6.5E-07 | 7.8 | 2.7 |
278 | mitotic cell cycle | 2.2E-08 | 9.3E-07 | 11.4 | 5.1 |
6351 | transcription, DNA-dependent | 2.4E-08 | 9.8E-07 | 11.2 | 4.9 |
6302 | double-strand break repair | 2.5E-08 | 9.8E-07 | 4.3 | 1.0 |
34470 | ncRNA processing | 3.4E-08 | 1.3E-06 | 11.2 | 5.0 |
65004 | protein-DNA complex assembly | 1.1E-07 | 3.7E-06 | 5.9 | 1.9 |
723 | telomere maintenance | 2.0E-05 | 3.7E-04 | 3.4 | 1.0 |
6395 | RNA splicing | 2.4E-05 | 4.4E-04 | 5.7 | 2.4 |
7059 | chromosome segregation | 4.0E-04 | 5.0E-03 | 5.3 | 2.5 |
51656 | establishment of organelle localization | 3.9E-03 | 3.4E-02 | 2.5 | 1.0 |
7127 | meiosis I | 4.4E-03 | 3.8E-02 | 3.0 | 1.3 |