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Figure 1 | BMC Systems Biology

Figure 1

From: Mathematical model of uptake and metabolism of arsenic(III) in human hepatocytes - Incorporation of cellular antioxidant response and threshold-dependent behavior

Figure 1

Schematic depiction of the cellular level TK model for rat hepatocytes. The solid lines that cross the cellular membrane (oval) represent transport processes, while the solid lines within the oval represent biotransformation. The dashed line represents the inhibitory effect of iAsIII on the second methylation reaction (MMA to DMA) (Source: Easterling et al. [34])

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BMC Systems Biology

ISSN: 1752-0509

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