Skip to main content

Table 1 List of top 13 transcription factors

From: Regulation of the yeast metabolic cycle by transcription factors with periodic activities

TF Periodicity Phase Amplitude Function
ACE2 0.520 45° 0.048 Cell cycle (early G1 specific transcription).
ADR1 0.518 48° 0.047 Glucose repression.
ARO80 0.544 44° 0.066 Aromatic AA degradation
BAS1 0.562 293° 0.082 Recombination. Purine and histidine synthesis.
GAL3 0.452 215° 0.036 Galactose metabolism.
GCN4 0.548 0.085 Main regulator of general AA control.
HAP1 0.449 80° 0.049 Respiration. Heme-responsive. Growth potential.
HAP3 0.503 255° 0.048 Respiration. Subunit of heme-activ'd Hap2/3/4/5.
HAP4 0.620 227° 0.124 Respiration. Subunit of heme-activ'd Hap2/3/4/5.
MSN4 0.595 0.062 Cell cycle. Stress-responsive gene expression.
RLR1 0.515 42° 0.063 Recombination. Transcriptional elongation.
SPT2 0.497 302° 0.108 Cell cycle (interacts w/histones, SWI-SNF).
SWI6 0.631 225° 0.058 Cell cycle (progression from G1 to S phase).
  1. Shown are the transcription factors that remain after iterative filtering for the highest periodicity scores of their α-coefficients. Phase and amplitude were calculated from the best-fit sine waves.