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Figure 3 | BMC Systems Biology

Figure 3

From: An experimentally-supported genome-scale metabolic network reconstruction for Yersinia pestis CO92

Figure 3

Analysis of possible defects within the Y. pestis CO92 rhamnose, melibiose, and glycerol uptake pathways. Epidemic Y. pestis strains such as CO92 cannot utilize rhamnose, and YP CO92 cannot ferment glycerol. The dashed line indicates a reaction catalyzed by GlpD (YPO3937) that is present in most other Enterobacteria but appears to be absent in YP CO92 due to a disruption in an underlying gene. Abbreviations: rham, rhamnose; 1-P, 1-phosphate; 3-P: 3-phosphate; DHAP, dihydroxyacetone phosphate; melib, melibiose; glc-D, D-glucose; galact, galactose; glyc, glycerol; OMP, outer membrane porin. The suffixes [e], [p], and [c] denote metabolites located in extracellular, periplasmic, and cytoplasmic compartments, respectively.

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