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Table 3 Metabolic fluxes corresponding to the best fit of experimental data and their 99% confidence intervals

From: Compartmentation of glycogen metabolism revealed from 13C isotopologue distributions

  Glucose as the only substrate Glucose with lactate  
  99% confidence interval 99% confidence interval  
  bestfit (min - max) bestfit (min - max) Model A
hk1 0.0026894(0.002150-0.003080) 0.152266(0.074815-0.377413) 0.01981
hk2 0.0021436(0.001710-0.002480) 0.0056939(0.0041563-0.0076078)  
g6pase1 5.50E-05(2.70E-5-7.80E-5) 0.150611(0.073125-0.375565) 0.01809
g6pase2 2.13E-05(0.0-0.000066) 0.005166(0.0029064-0.0071982)  
pfk1 0.003048(0.002370-0.003530) 0.0023558(0.0015063-0.0046942) 0.00345
pfk2 0.0004816(0.0-0.000950) 0.0007975(0.0006197-0.0012778)  
fbpase1 0.0004446(0.000270-0.000560) 0.0013469(0.0005781-0.0023709) 0.00363
fbpase2 0.0005496(0.000330-0.000690) 0.0023329(0.00161-0.0032427)  
gp 2.56E-06(1.70E-6-5.10E-6) 0.000143(5.12E-05-0.0001883) 0.00000
gs 0.0021929(0.001660-0.002680) 0.0022087(0.0018593-0.0027097) 0.00188
aldf 0.0192413(0.007480-0.022580) 0.0159083(0.0153142-0.0163931) 0.01608
aldr 0.016706(0.004480-0.020410) 0.0164349(0.0153054-0.016708) 0.01625
aldex 0.0424386(0.010420-0.056150) 0.0137425(0.0103922-0.0195718) 0.01565
g3pep 0.0064103(0.004490-0.007700) 0.258278(0.1677705-0.3394195) 0.12224
pepg3 0.0013391(0.000140-0.002370) 0.258701(0.166264-0.339572) 0.12257
pk 0.0050704(0.003910-0.006230) 0.0199774(0.0157079-0.0239355) 0.01497
lacin 1.71E-07(1.20E-7-2.60E-7) 0.231716(0.1714965-0.2686475) 0.12266
lacout 0.00507(0.003910-0.006230) 0.222326(0.1621185-0.2590095) 0.11074
pc 1.20E-07(5.70E-8-1.90E-7) 0.0204457(0.0155337-0.0233495) 0.01542
pepck 1.16E-08(5.30E-9-2.80E-8) 0.020401(0.0154933-0.0232863) 0.01530
maloa 1.85E-07(9.60E-8-3.00E-7) 0.0835934(0.048937-0.111892) 0.03396
oamal 3.80E-08(1.30E-8-8.10E-8) 0.0747156(0.0368199-0.0997713) 0.02261
cs 2.55E-07(1.30E-7-4.00E-7) 0.008922(0.0069631-0.0147641) 0.01147
citmal 1.47E-07(8.40E-8-2.30E-7) 0.0088778(0.0069227-0.0146991) 0.01135
pdh 2.75E-07(7.70E-8-5.00E-7) 0.0089212(0.0069623-0.0147633) 0.01147
g6pdh 3.87E-06(2.80E-6-7.50E-6) 0.0018986(0.0013506-0.0021492) 0.00000
p5p > s7p 0.0011849(0.000880-0.002270) 0.0006229(0.0004459-0.0007215) 0.00051
s7p > r5p 0.0011925(0.000890-0.002280) 4.35E-06(2.56E-06-2.98E-05) 0.00047
f6p > p5p 9.59E-06(4.20E-6-3.40E-5) 4.02E-05(1.17E-05-9.84E-05) 0.00000
p5p > f6p 4.93E-06(2.80E-6-2.80E-5) 0.0006793(0.0004937-0.000751) 0.00000
f6p > s7p 1.85E-05(9.20E-6-7.30E-5) 1.40E-05(4.56E-06-2.45E-05) 0.00000
s7p > f6p 9.56E-06(4.80E-6-6.60E-5) 1.65E-06(9.03E-07-8.56E-06) 0.00000
p5p-g3p 0.0006152(2.70E-4-2.83E-3) 0.0017868(0.0007706-0.0033249) 0.00036
f6p-s7p 7.69E-08(2.10E-8-7.70E-7) 1.53E-05(4.62E-06-2.78E-05) 0.00000
p5p-s7p 0.0022967(1.37E-3-7.06E-3) 1.51E-06(8.37E-07-8.16E-06) 0.00067
f6p > s7p 0.0015144(0.000850-0.001940) 0.000862(0.0002796-0.0021263) 0.00117
s7p-f6p 0.0015015(0.000850-0.001920) 0.0014894(0.0008194-0.0026708) 0.00119
f6p-g3p 0.0075338(0.002170-0.013330) 0.0164459(0.0085357-0.0352201) 0.00230
s7p-e4p 0.0003018(0.000140-0.000550) 7.81E-05(2.01E-05-0.0002102) 0.00061
  1. The names of fluxes are given in the list of abbreviations in the text.
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