Figure 2
Escherichia coli core and pangenome metabolic network evolution according to the number of sequenced genomes listed in table 2. Number of conserved genes (black diamonds), total number of unique genes without orthologs in prior genomes (blue squares), and total number of gene additions to the pan-GEM (red triangles), and total number of metabolic reactions additions to the pan-GEM (green circles) for a given number of genomes analyzed for the different strains of E. coli.