Figure 4

Validation of putative MYB targets with siRNA treatments. Top: qRT-PCR measurements of c-myb mRNA levels in the K562 leukemia cell line without treatment (left), treated with the siRNA against c-myb (middle), and treated with the siRNA against GFP (right). Bottom: Relative mRNA levels of selected genes under the c-myb siRNA treatment with respect to the qRT-PCR measurements under the control siRNA treatment. Green bars: expression responses of putative MYB targets. Blue bars: expression responses of control genes.