Distribution of fluxes in the central metabolic network of M. extorquens AM1 upon methylotrophic growth. Carbon fluxes were calculated from 183 isotopomer measurements (NMR + MS data) collected during steady-state growth of M. extorquens AM1 on [13C]-methanol. Fluxes are given in mmol · g-1 · h-1, with standard deviations given below flux values. Exchange fluxes through reversible reactions are given within brackets. The width of the arrows is proportional to the flux value.