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Table 1 Data sets included in the host response compendium

From: A chemokine gene expression signature derived from meta-analysis predicts the pathogenicity of viral respiratory infections

Virus Virus strain Mouse strain Time points* Outcome Reference
Influenza A H1N1 r1918, 2:6 r1918 (1918 HA, NA in Tx91), 5:3 r1918 (1918 HA, NA, M, NP, S in Tx91), Tx91 (A/Texas/36/91) BALB/c 1, 3, 5 dpi 0% survival (with r1918, 2:6 r1918, 5:3 r1918), 100% survival (with Tx91) Kash 2006 [30], Tumpey 2005 (for outcome data)[31]
Influenza A H1N1 r1918, PR8 C57BL/6 1, 3, 5 dpi 0% survival (with r1918), 65% survival (with PR8) Goodman 2009 [32]
Influenza A H3N2 HKx31 (A/HKx31) BABL/c, C57BL/6 30 hpi 45% survival (in BALB/c), 80% survival (in C57BL/6) Ding 2008 [33], Toth 1995 (for outcome data)[34]
Influenza A H5N1 HK213 (A/Hong Kong/213/03) C57BL/6, DBA/2J, 3 dpi 0% survival (in DBA/2J), 30% survival (in C57BL/6) Boon 2009 [35]
Influenza A H5N1 HK483 (A/HK/483/97), HK486 (A/HK/486/97), HK486PB2MT (A/HK/486 PB2-627K/97) BALB/c 2, 4 dpi 0% survival (with HK483, HK486PB2MT), 25% (with HK486) Fornek 2009 [36]
Influenza A H5N1 VN/1203 (Vietnam/1203/04), r1918 (H1N1) SvEv129 1, 3, 4 dpi 0% survival (with VN/1203, r1918) Cilloniz 2010 [37]
Mengovirus vMC0 (UV-inactivated mengovirus) BALB/c 18 hpi 100% survival Rosenthal unpub.
RSV A2 BALB/c 1, 3 dpi 100% survival Janssen 2007 [38]
RSV A2 B6:129PF1/J 1 dpi 100% survival Minor 2010 [39]
SARS-CoV Urbani BALB/c (young, aged) 1, 2, 5, 7 dpi 100% survival (in young, aged) Baas 2008 [40]
SARS-CoV icUrbani, icGZ02, icHC/SZ/61/03 BALB/c AnNHsd (young, aged) 12 h, 1, 3 dpi 0% survival (in aged with icHC/SZ/61/03), 40% survival (in aged with icGZ02), 100% survival (in young with all 3 virus strains, in aged with Urbani) Rockx 2009 [41]
SARS-CoV MA15 129 2, 5, 9 dpi 100% survival Zornetzer 2010 [42]
Influenza A H1N1 A/CA/04/2009, MA1 (a mouse-adapted strain of A/CA/04/2009) BALB/c 1, 3, 5 dpi 0% survival (with MA1), 100% survival (with A/CA/04/2009) Josset in preparation
  1. * Note "dpi" refers to days post-infection. Other annotations are stated as in primary publications. The last row (below line) refers to a data set external to the compendium that was used as a test set for predictions.