Figure 1
From: Heterogeneity reduces sensitivity of cell death for TNF-Stimuli
Illustration of the Signaling Pathways and Interactions Initiated by TNF-R1. Ligand stimulated TNF-R1 activates two major signaling pathways, pro- and anti-apoptotic cellular responses (red and blue background, respectively). The ligand-receptor interaction and signal complex formation is outlined in the green area.