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Table 1 Impact of the NF-κB Pathway

From: Heterogeneity reduces sensitivity of cell death for TNF-Stimuli

  TNF 30 ng/ml 10 ng/ml 3 ng/ml 1 ng/ml
Continuous Death rate +1.46% +1.59% +2.93% +8.15%
  Median time of death -6.25% -6.85% -8.55% -10.6%
  Relative std -57.9% -53.3% -34.1% -18.3%
Pulse Death rate +11.7% +13.5% +19.0% +35.2%
  Median time of death +0.99% +0.37% +3.27% +3.52%
  Relative std +3.84% +8.91% -2.72% -0.80%
  1. Comparison of NF-κB knockout cells and wild type cells for different stimulations (continuous and 30 minute pulse of TNF at concentrations of 1, 3, 10 or 30 ng/ml). Death rate, median time of death and standard deviation normalized by the median (relative std) are shown here for the knockout cells normalized by the corresponding wild type cell value.