Theoretical basis of the community effect in development

BMC Systems Biology

Table 2 Noise in gene expression depends on community size and communication rate ε

Community size (cell number)	ε (sec ^-1)	Mean	Standard deviation	Noise
200	2.31 × 10 ^-6	260.8	70.0	0.268
200	5.78 × 10 ^-7	87.7	43.1	0.492
300	5.78 × 10 ^-7	146.6	54.7	0.373
500	5.78 × 10 ^-7	212.7	63.7	0.300

Noise (coefficient of variation = standard deviation/mean) in gene expression was calculated from the steady state distribution of [Ap]*, which was derived from the stochastic simulations with one copy each of genes A and B, and with parameter values as listed in Table 1.

ISSN: 1752-0509