Figure 3
From: Improved functional overview of protein complexes using inferred epistatic relationships
Novel inter-complex edges generated by newly-inferred epistatic interactions: Nodes represent protein complexes (as cataloged by Pu et al [57]) while edges represent strong net positive or net negative genetic interactions between complexes. Grey edges represent interactions which are unaffected by our predicted interactions, violet edges represent interactions which have been given additional links by our predicted interactions, and red edges represent previously unreported interactions between complexes, established using our method. Edges are only drawn if the median genetic interaction is significantly more positive or negative than one would expect by chance (P < 0.001)