Figure 6

Stability index curves (A)-(C): Plots of the stability indices for various values of ω _j ∈ (–1000,1000) for j = 1, 2, 3. A stability index value of –1 and +1 indicates stable and unstable responses of gene and protein expression in time, respectively. The value ω _j < 0 represents repressing feedback and ω _j > 0 is the activating feedback effect. Simulations performed using parameters from System specification and the pseudo steady state expression values at which the Jacobian is estimated.