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Table 1 Estimated size and power (no replicates for each condition).

From: Statistical methods on detecting differentially expressed genes for RNA-seq data

Lambda1 Lambda2 LRT Cond Wald Wald-Log VST Fisher
5 5 0.0128 0.0002 0.0002 0.0185 0.0011 0.0002
  9 0.0199 0.0066 0.0074 0.0522 0.0176 0.0066
  13 0.0842 0.0492 0.0550 0.1737 0.0916 0.0492
  17 0.2484 0.1877 0.1964 0.3976 0.2626 0.1877
  21 0.4903 0.4248 0.4358 0.6269 0.4981 0.4248
  25 0.7146 0.6547 0.6685 0.8077 0.7168 0.6547
10 10 0.0013 0.0004 0.0005 0.0041 0.0013 0.0004
  15 0.0114 0.0082 0.0089 0.0256 0.0124 0.0082
  20 0.0729 0.0504 0.0571 0.1190 0.0737 0.0504
  25 0.2433 0.1863 0.2110 0.3217 0.2435 0.1863
  30 0.4848 0.4111 0.4460 0.5746 0.4848 0.4111
  35 0.7177 0.6625 0.6900 0.7859 0.7177 0.6625
  40 0.8750 0.8414 0.8599 0.9102 0.8750 0.8414
15 15 0.0012 0.0007 0.0009 0.0030 0.0012 0.0007
  20 0.0075 0.0047 0.0052 0.0140 0.0075 0.0047
  25 0.0456 0.0314 0.0377 0.0689 0.0456 0.0314
  30 0.1483 0.1130 0.1305 0.1990 0.1483 0.1130
  35 0.3422 0.2868 0.3167 0.4121 0.3422 0.2868
  40 0.5692 0.5046 0.5459 0.6266 0.5692 0.5046
  45 0.7563 0.7047 0.7393 0.8002 0.7563 0.7047
  50 0.8907 0.8569 0.8796 0.9096 0.8907 0.8569
30 30 0.0011 0.0007 0.0011 0.0019 0.0011 0.0007
  40 0.0180 0.0125 0.0163 0.0224 0.0180 0.0125
  50 0.1464 0.1167 0.1370 0.1704 0.1464 0.1167
  60 0.4776 0.4292 0.4620 0.5109 0.4777 0.4292
  70 0.7840 0.7526 0.7750 0.8145 0.7848 0.7526
  80 0.9421 0.9299 0.9390 0.9514 0.9423 0.9299
  1. Estimated size and power from each method for detecting the difference of two Poisson means. There are no replicates for each condition. The Poisson means for the first condition are 5, 10, 15, or 30. The second Poisson means are the same as (for size) or larger than (for power) the first ones. The nominal size (significance level) is 10-3 and 10,000 runs are used for each setting.