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Table 3 Number of transcription factors with gene sets containing their known binding sites enriched by the different methods in comparison

From: Integrating external biological knowledge in the construction of regulatory networks from time-series expression data

Method

Data used

# TFs with enriched gene setsa

iBMA-prior

Gene expression + external data

38

iBMA-shortlist

Gene expression + external data

30

LASSO-shortlist

Gene expression + external data

41

LAR-shortlist

Gene expression + external data

44

iBMA-size

Gene expression data only

4

iBMA-noprior

Gene expression data only

9

LASSO-noprior

Gene expression data only

13

LAR-noprior

Gene expression data only

10

  1. a FDR was controlled at 10%.
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BMC Systems Biology

ISSN: 1752-0509

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