Table 1 Parameters of ER binding with ligands and DNA ERE

ER+ER=ER₂

K1

25

>50

[73]

ER₂+H=ER₂H

K2

0.2

0.16

[23]

ER₂H+H=ER₂H₂

K3

0.1

-

ER+H=ERH

K4

0.25

0.9

[31]

ERH+ER=ER₂H

K5^*

20

50

[73]

ERH+ERH=ER₂H₂

K6^*

8

4

[33]

20

[73]

ER₂+I=ER₂I

K7

10

-

ER₂I+I=ER₂I₂

K8

150

220

[31]

ER+I=ERI

K9

30

-

ERI+ER=ER₂I

K10^*

8.3

< K5

[23]

ERI+ERI=ER₂I₂

K11^*

41.5

-

ERH+ERI=ER₂HI

K12^*

26.67

-

ER₂I+H=ER₂HI

K13

0.8

-

ER₂H+I=ER₂HI

K14^*

40

-

ER₂+D=ER₂D

K15

8

40

[35]

2.5

[36]

ER₂H+D=ER₂HD

K16

2.4

-

ER₂H₂+D=ER₂H₂D

K17

1.2

1.8 ±0.6

[36]

2.0±0.3

[27];

10

[35]

ER₂I+D=ER₂ID

K18

50

-

ER₂I₂+D=ER₂I₂D

K19

87

14

[37]

ER₂HI+D=ER₂HID

K20

10-20

-