From: Incremental parameter estimation of kinetic metabolic network models
Simultaneous method | Incremental method | |||
---|---|---|---|---|
| min Φ S | min Φ C | min Φ S | |
CPU time (sec) | 85.03 h | 4002.01 ± 696.11 | 1404.22 ± 120.71 | 445.47 ± 35.94 |
eSSM GO iterations | 308 | 365 ± 91 | 67 ± 10 | 48 ± 10 |
Parameter error (%) | 71.90 | 43.50 ± 2.34 | 68.85 ± 4.57 | 40.47 ± 0.59 |
Φ C | 4.54 × 10 -3 | 6.46 × 10-3 ± 4.08 × 10-4 | 3.38 × 10-3 ± 1.14 × 10-4 | 5.94 × 10-3 ± 3.23 × 10-5 |
Φ S | 1.03 | 2.99 × 10-2 ± 3.82 × 10-4 | 8.32 × 10-2 ± 4.04 × 10-3 | 2.94 × 10-2 ± 2.77 × 10-6 |