Table 3 Recon 1 metabolic pathways differentially represented in brain and non-brain normal tissues
From: Reconstruction of genome-scale metabolic models for 126 human tissues using mCADRE
Pathwaysa | % complete in brain models | % complete non-brain models | Rank sum p-value |
|---|---|---|---|
Taurine and hypotaurine metabolism | 66% | 35% | 4.14E-08 |
Fatty acid elongation | 67% | 37% | 1.69E-09 |
Tyr, Phe, Trp Biosynthesis | 77% | 56% | 4.96E-02 |
Salvage Pathway | 94% | 81% | 2.26E-02 |
Cysteine Metabolism | 50% | 37% | 3.61E-03 |
Alanine and Aspartate Metabolism | 73% | 61% | 2.41E-09 |
Glutamate metabolism | 86% | 76% | 1.59E-06 |
Butanoate Metabolism | 32% | 23% | 9.34E-03 |
Valine, Leucine, and Isoleucine Metabolism | 69% | 61% | 4.00E-02 |
Transport, Nuclear | 33% | 25% | 2.05E-11 |