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Table 2 Residual sum of squares values for each metabolite

From: Dynamic regulatory on/off minimization for biological systems under internal temporal perturbations

Method

Metabolite

    
 

RuBP

PGA

DPGA

GAP

Ru5P

Sink

DFBA

20.07

2.21

16.15

2.55

3.55

224.86

M-DFBA

28.02

7.58

13.33

2.54

3.20

567.42

Flux-based M-DFBA

36.66

2.32

17.28

2.22

3.57

534.20

M-DFBA CF

15.45

28.17

18.98

2.15

3.54

564.26

R-DFBA NLP

1.35

76.20

8.93

3.91

22.24

582.23

Flux-based R-DFBA NLP

14.38

345.25

13.68

2.35

5.66

558.03

R-DFBA CF NLP

1.86

14.97

7.28

3.57

23.53

582.23

R-DFBA MINLP

3.80

67.25

11.72

3.17

0.61

129.49

Flux-based R-DFBA MINLP

18.17

0.66

9.76

2.50

18.85

497.71

R-DFBA CF MINLP

9.80

5.17

5.84

3.01

55.48

420.66

  1. The discrepancy between the kinetic modeling results and the results obtained from the DFBA-based approaches is quantified based on the residual sum of squares