Table 1 Information of the novel molecular targets
From: Predicting new molecular targets for rhein using network pharmacology
GeneID Entry | Gene name | Disease | Pathway |
|---|---|---|---|
4313 | MMP2 | Cancer | GnRH signaling pathway |
| Â | Â | Choriocarcinoma | Leukocyte transendothelial migration |
| Â | Â | Torg-Winchester syndrome | Pathways in cancer |
4318 | MMP9 | Penile cancer | Pathways in cancer |
| Â | Â | Metaphyseal dysplasias | Leukocyte transendothelial migration |
| Â | Â | Â | Transcriptional misregulation in cancer |
7124 | TNF | Asthma | MAPK signaling pathway |
| Â | Â | Systemic lupus erythematosus | Cytokine-cytokine receptor interaction |
| Â | Â | Malaria | Natural killer cell mediated cytotoxicity |
| Â | Â | Pertussis | NOD-like receptor signaling pathway |
| Â | Â | Type I, II diabetes mellitus | Toll-like receptor signaling pathway |
| Â | Â | Alzheimer's disease | RIG-I-like receptor signaling pathway |
| Â | Â | Amoebiasis | Natural killer cell mediated cytotoxicity |
| Â | Â | Tuberculosis | T cell receptor signaling pathway |
| Â | Â | Hepatitis C | Fc epsilon RI signaling pathway |
| Â | Â | Influenza A | Apoptosis |
| Â | Â | HTLV-I infection | TGF-beta signaling pathway |
| Â | Â | Herpes simplex infection | Natural killer cell mediated cytotoxicity |
| Â | Â | Cardiovascular Diseases; | Hematopoietic cell lineage |