Figure 3

${\mathit{R}}_{\mathit{\infty }}^{{\mathit{K}}_{\mathit{t}}}$and n _H for the basic model. (a) $R_{\infty }^{K_t}$ is computed analytically as S _t /P _t , α and λ₁/λ₂ is varied. Baseline parameter values used for the basic model, are: λ₋₁ = 1 s⁻¹,λ₁ = 1 M⁻¹s⁻¹,k₁ = 1 s⁻¹,λ₋₂ = 1 s⁻¹,λ₂ = 1μ M⁻¹s⁻¹,k₂ = 0. 01 s⁻¹,P _t = 1μ M,S _t = 10μ M.(b) n _H is computed analytically as S _t /P _t , α and λ₁/λ₂is varied. Baseline parameter values used for the basic model are: λ₋₁ = 1 s⁻¹,λ₁ = 1μ M⁻¹s⁻¹,k₁ = 1 s⁻¹,λ₋₂ = 1 s⁻¹,λ₂ = 1μ M⁻¹s⁻¹,k₂ = 1 s⁻¹,P _t = 1μ M,S _t = 100μ M.