Skip to main content
Figure 3 | BMC Systems Biology

Figure 3

From: Bell-shaped and ultrasensitive dose-response in phosphorylation-dephosphorylation cycles: the role of kinase-phosphatase complex formation

Figure 3

R K t and n H for the basic model. (a) R K t is computed analytically as S t /P t , α and λ1/λ2 is varied. Baseline parameter values used for the basic model, are: λ−1 = 1 s−1,λ1 = 1 M−1s−1,k1 = 1 s−1,λ−2 = 1 s−1,λ2 = 1μ M−1s−1,k2 = 0. 01 s−1,P t = 1μ M,S t = 10μ M.(b) n H is computed analytically as S t /P t , α and λ1/λ2is varied. Baseline parameter values used for the basic model are: λ−1 = 1 s−1,λ1 = 1μ M−1s−1,k1 = 1 s−1,λ−2 = 1 s−1,λ2 = 1μ M−1s−1,k2 = 1 s−1,P t = 1μ M,S t = 100μ M.

Back to article page