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Figure 2 | BMC Systems Biology

Figure 2

From: Metabolic network analysis predicts efficacy of FDA-approved drugs targeting the causative agent of a neglected tropical disease

Figure 2

Pipelines for prioritization of targets and drugs. The funnel diagrams in panels A and B depict the specific datasets, tools and cutoffs used in the process of prioritization. Panel A presents the prioritization scheme that includes single gene deletions as a constraint, while Panel B presents the prioritization scheme that includes double gene deletions (or synthetic lethality) as a constraint.

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