Figure 2From: Metabolic network analysis predicts efficacy of FDA-approved drugs targeting the causative agent of a neglected tropical diseasePipelines for prioritization of targets and drugs. The funnel diagrams in panels A and B depict the specific datasets, tools and cutoffs used in the process of prioritization. Panel A presents the prioritization scheme that includes single gene deletions as a constraint, while Panel B presents the prioritization scheme that includes double gene deletions (or synthetic lethality) as a constraint.Back to article page