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Table 7 False negative model predictions due to misidentified experiment phenotypes or media compositions

From: Gap-filling analysis of the iJO1366 Escherichia coli metabolic network reconstruction for discovery of metabolic functions

Gene

Explanation

mtn (b0159)

essential according to Choi-Rhee et al. [36]

thiI (b0423)

possibly thiamin in media due to incomplete washing

bioA (b0774)

possibly biotin in media due to incomplete washing

bioB (b0775)

possibly biotin in media due to incomplete washing

bioF (b0776)

possibly biotin in media due to incomplete washing

bioC (b0777)

possibly biotin in media due to incomplete washing

bioD (b0778)

possibly biotin in media due to incomplete washing

aroD (b1693)

only experimental growth under one condition, possible error

thiD (b2103)

essential according to Orth et al. [10]

cysD (b2752)

only experimental growth under one condition, possible error

argG (b3172)

only experimental growth under one condition, possible error

cysG (b3368)

only experimental growth under one condition, possible error

bioH (b3412)

possibly biotin in media due to incomplete washing

ilvE (b3770)

only experimental growth under one condition, possible error

thiH (b3990)

essential according to Orth et al. [10]

thiG (b3991)

essential according to Orth et al. [10]

thiF (b3992)

essential according to Orth et al. [10]

thiE (b3993)

essential according to Orth et al. [10]

thiC (b3994)

essential according to Orth et al. [10]

cysQ (b4214)

MOPS is a possible alternate S source