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Table 1 Experimental conditions used for validation

From: A genome-scale metabolic model of the lipid-accumulating yeast Yarrowia lipolytica

Reference

Gene KOs

Media conditions

BioloMICS[16]

–

46 different carbon sources

Thevenieau,2007[10]

15 gene KOs

YNBD, YNBO, YNBC10, YNBC16, YNBT

T van den Temple, 2000[17]

–

Lactose, D-Galactose

Jardon, 2008[18]

FBP1

YNBD, Ethanol, Glycerol, Acetate

Flores, 2005[19]

PYC1, ICL1

YNBD, Ethanol, Aspartate, Glutamate

Yamagami, 2001[20]

PAT1

YNBC10, YNBD, Glycerol

Haddouche (PC)[21]

ACL1

YNBD, YNBO

Kabran, 2010[22]

ICL1, MLS1, CIT2

Acetate, YNBO, YNBD

Beopoulos, 2008[23]

GUT2, POX1-6

YNBD, Glycerol, YNBO

Jiménez-Bremont, 2001[24]

OCD1

YNBD, YNBD + putrescine

Cheon, 2003[25]

TRP1

YNBD, YNBD + tryptophane

  1. Literature sources used for validation of the Y. lipolytica model. Overall, 60 different media conditions were tested. Gene knockouts were assessed for 29 different Y. lipolytica gene loci, in 152different experiments. Only those cases where evident growth/no growth was observed were included in this analysis.