From: A systems biology approach reveals common metastatic pathways in osteosarcoma
Gene Symbol | Accession # | LM7/ SaOS-2 | p-value | Unique Peptides | Function |
---|---|---|---|---|---|
VIM | IPI00418471 | 350 | 1 x 10E-42 | 22 | Filaments expressed in neoplasms originated from mesenchymal cells |
TPM1 | IPI00940084 | 130 | 2.2 x 10E-41 | 2 | Contractile system of muscles and the cytoskeleton of non-muscle cells |
ALB | IPI00022434 | 120 | 2 x 10E-38 | 9 | Primarily a carrier protein in serum |
ODZ3 | IPI00398020 | 97 | 1.1 x 10E-30 | 2 | May function as signal transducer |
KRT5 | IPI00009867 | 90 | 1.4 x 10E-28 | 2 | Filaments found in basal layer of epidermis |
WDR49 | IPI00216853 | 86 | 2.7 x 10E-27 | 2 | Regulates cell division, cell-fate determination, gene transcription, and transmembrane signaling |
A2M | IPI00478003 | 84 | 1.9 x 10E-26 | 6 | Inhibits all classes of proteinases by a unique 'trapping' mechanism |
NES | IPI00010800 | 81 | 1.3 x 10E-25 | 16 | Disassembly of vimentin, role in the trafficking and distribution of cellular factors during progenitor cell division |
CAL2 | IPI00916600 | 70 | 3.4 x 10E-22 | 3 | Mediates the control of numerous enzymes and proteins by calcium |
ANXA5 | IPI00329801 | 58 | 2.4 x 10E-18 | 6 | Anticoagulant, inhibitor of the thromboplastin-specific complex |