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Table 3 Yeast 5 and Yeast 4 simulated flux predictions

From: Yeast 5 – an expanded reconstruction of the Saccharomyces cerevisiae metabolic network

 

yeast 5

yeast 4

Sample FBA flux predictions

  

glucose-limited, aerobic growth rate

0.09

0.17

glucose-limited, anaerobic growth rate

0.02

0

aerobic flux through glycolysisa

1.33

0.89

anaerobic flux through glycolysis

1.85

-

aerobic flux through TCA cycleb

1.06

0.01

anaerobic flux through TCA cycle

0

-

aerobic ethanol production

0

0

anaerobic ethanol production

1.74

-

  1. Fluxes are normalized to the glucose uptake flux, which is set to 1 mmol/g dry weight/h.
  2. aglycolysis flux measured through pyruvate kinase.
  3. bTCA cycle flux measured through malate dehydrogenase.
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BMC Systems Biology

ISSN: 1752-0509

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