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Table 2 Carbon consumption and derived secondary metabolite production yields in the time period 45–50 hrs

From: Optimized submerged batch fermentation strategy for systems scale studies of metabolic switching in Streptomyces coelicolor A3(2)

Ferm. # Carbon source consumption Yields [%Cmol]
D-glucose L-glutamate RED γ-Act TBP
Cmol/L-h Cmol/L-h Cmol RED/Cmol C source Cmol ACT/Cmol C source Cmol TBP/Cmol C source
18a 0.0059 0.0238 1.0 0.4 1.0
19a 0.0083 0 0.1 2.2 4.9
  1. Carbon consumption and derived secondary metabolite production yields determined for one representative cultivation each of experiments with high resolution time-series sampling for full-scale ‘omics analysis using the fully developed media and conditions for studying the effect of phosphate (ferm. #18a) and L-glutamate depletion (ferm. #19a), respectively, on metabolic switching by strain M145. Results from ‘omics analyses partly presented earlier [1922] or to be published elsewhere.