Skip to main content

Table 3 Covariance matrix C for the Michaelis-Menten reaction system.

From: Biochemical fluctuations, optimisation and the linear noise approximation

  S SE P E
S 1455.82 (1455.57) 61.35 (61.23) 33.46 (32.80) -61.35 (-61.23)
SE 61.35 (61.23) 59.09 (59.07) -4.36 (-4.43) -59.09 (-59.07)
P 33.46 (32.80) -4.36 (-4.43) 773.86 (773.41) 4.36 (4.43)
E -61.35 (-61.23) -59.09 (-59.07) 4.36 (4.43) 59.09 (59.07)
  1. The convariance matrix C for the Michaelis-Menten reaction system. Reaction parameters were chosen to be k1 = 0.2 nMs-1, k2 = 4 nM-1s-1, k3 = 3 s-1, k4 = 1 s-1, k5 = 0.15 s-1. The system volume was 10-12 l. The covariances calculated using the LNA was compared with those obtained from simulation (values in brackets) using 104 time series generated using the Gillespie algorithm (Direct Method) in COPASI