Table 3 Overlap and different proteins identified by ION and eight other existing centrality methods
Centrality measures (Mi) | |ION∩Mi| | |Mi − ION| | nonessential proteins in {Mi − ION} | non-essential proteins percentage in {Mi − ION} with low ION value |
|---|---|---|---|---|
Degree Centrality (DC) | 1 | 99 | 54 | 59.26% |
Betweenness Centrality (BC) | 1 | 99 | 56 | 57.14% |
Closeness Centrality (CC) | 0 | 100 | 59 | 55.93% |
Subgraph Centrality(SC) | 1 | 99 | 63 | 52.38% |
Eigenvector Centrality(EC) | 1 | 99 | 63 | 52.38% |
Information Centrality(IC) | 0 | 100 | 56 | 55.36% |
Edge Clustering Coefficient Centrality (NC) | 14 | 86 | 42 | 73.81% |
PCC and ECC centrality(PeC) | 27 | 73 | 24 | 45.83% |