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Table 4 Enriched KEGG pathway of mouse cBIP and sBIP gene classes.

From: The preservation of bidirectional promoter architecture in eukaryotes: what is the driving force?

KEGG pathway ID Pathway Name p-value gene type
mmu03040* Spliceosome 3.30E-03 cBIP
mmu04110 Cell cycle 3.70E-03 cBIP
mmu04142 Lysosome 4.13E-03 cBIP
mmu03018* RNA degradation 5.70E-03 cBIP
mmu00970 Aminoacyl-tRNA biosynthesis 8.74E-03 cBIP
mmu03020* RNA polymerase 8.97E-03 cBIP
mmu00190 Oxidative phosphorylation 1.07E-02 cBIP
mmu03440 # Homologous recombination 1.36E-02 cBIP
mmu00052 Galactose metabolism 1.59E-02 cBIP
mmu05012 Parkinson's disease 1.98E-02 cBIP
mmu04146 Peroxisome 3.03E-02 cBIP
mmu03420 # Nucleotide excision repair 3.30E-02 cBIP
mmu00240 Pyrimidine metabolism 6.22E-03 sBIP
mmu03020* RNA polymerase 5.15E-03 sBIP
mmu00062 Fatty acid elongation in mitochondria 1.10E-02 sBIP
mmu00903 Limonene and pinene degradation 1.40E-02 sBIP
mmu00280 Valine, leucine and isoleucine degradation 1.98E-02 sBIP
mmu05340 Primary immunodeficiency 4.08E-02 sBIP
mmu00860 Porphyrin and chlorophyll metabolism 4.96E-02 sBIP
  1. The two catteries of mouse bidirectional genes (cBIP, sBIP) were computed for the KEGG pathway enrichment respectively. cBIP represents the genes regulated by the human-mouse conserved bidirectional promoters, while the sBIP represents the genes in the species-specific bidirectional gene pairs. * Transcription and translation related pathways # DNA repair related pathways