Table 1 Results of functional enrichment analysis for three clusters.
From: Computational gene network analysis reveals TNF-induced angiogenesis
Category | Term | #genes | p-value |
|---|---|---|---|
Cluster A | |||
GOTERM_BP_FAT | GO:0008283: cell proliferation | 13 | 0.0027 |
GOTERM_BP_FAT | GO:0001775: cell activation | 10 | 0.0039 |
GOTERM_BP_FAT | GO:0006916: anti-apoptosis | 8 | 0.0070 |
GOTERM_BP_FAT | GO:0040007: growth | 7 | 0.0144 |
KEGG_PATHWAY | hsa05222: Small cell lung cancer | 5 | 0.0442 |
GOTERM_BP_FAT | GO:0001568: blood vessel development | 7 | 0.0497 |
Cluster B | |||
GOTERM_BP_FAT | GO:0007596: blood coagulation | 5 | 0.00034 |
GOTERM_BP_FAT | GO:0043066: negative regulation of apoptosis | 8 | 0.0056 |
GOTERM_BP_FAT | GO:0043069: negative regulation of programmed cell death | 8 | 0.0060 |
GOTERM_BP_FAT | GO:0060548: negative regulation of cell death | 8 | 0.0061 |
GOTERM_BP_FAT | GO:0045765: regulation of angiogenesis | 4 | 0.0066 |
GOTERM_BP_FAT | GO:0006916: anti-apoptosis | 6 | 0.0083 |
GOTERM_BP_FAT | GO:0008283: cell proliferation | 8 | 0.0164 |
KEGG_PATHWAY | hsa05200: Pathways in cancer | 8 | 0.0237 |
GOTERM_BP_FAT | GO:0016477: cell migration | 6 | 0.0260 |
PIR_SUPERFAMILY | PIRSF001719: fos transforming protein | 2 | 0.0334 |
GOTERM_BP_FAT | GO:0008284: positive regulation of cell proliferation | 7 | 0.0396 |
INTERPRO | IPR000837: Fos transforming protein | 2 | 0.0443 |
Cluster C | |||
GOTERM_BP_FAT | GO:0006916: anti-apoptosis | 9 | 0.0001 |
GOTERM_BP_FAT | GO:0043066: negative regulation of apoptosis | 11 | 0.0001 |
GOTERM_BP_FAT | GO:0043069: negative regulation of programmed cell death | 11 | 0.0001 |
GOTERM_BP_FAT | GO:0060548: negative regulation of cell death | 11 | 0.0001 |
INTERPRO | IPR011539: Rel homology | 3 | 0.0014 |
INTERPRO | IPR000451: NF-kappa-B/Rel/dorsal | 3 | 0.0014 |
GOTERM_BP_FAT | GO:0043123: positive regulation of I-kappaB kinase/NF-kappaB cascade | 5 | 0.0035 |
GOTERM_BP_FAT | GO:0043122: regulation of I-kappaB kinase/NF-kappaB cascade | 5 | 0.0050 |
BIOCARTA | h_nthiPathway: NFκB activation by Nontypeable Hemophilus influenzae | 4 | 0.0066 |
GOTERM_BP_FAT | GO:0016477: cell migration | 7 | 0.0087 |
GOTERM_BP_FAT | GO:0030155: regulation of cell adhesion | 5 | 0.0117 |
KEGG_PATHWAY | hsa05222: Small cell lung cancer | 5 | 0.0125 |
PIR_SUPERFAMILY | PIRSF037644: inhibitor of apoptosis protein with CARD domain | 2 | 0.0129 |
GOTERM_CC_FAT | GO:0033256: I-kappaB/NF-kappaB complex | 2 | 0.0233 |
KEGG_PATHWAY | hsa05200: Pathways in cancer | 9 | 0.0234 |
GOTERM_BP_FAT | GO:0030334: regulation of cell migration | 5 | 0.0235 |