Figure 3

The frequencies of abundant modified fragments in all libraries. Only the modification events with $\underset{-}{\ge }$ 1% frequency in all libraries were plotted. (a) The global patterns of modification events. (b,c) Several miRNAs have their specific patterns of modification events different from the global one. The expression level of hsa-miR-122 is much lower in SRX018971 than in other libraries, so that SRX018971 was not included in Figure 2a. (d) The patterns of modification events of some miRNAs are library specific.