IntPath--an integrated pathway gene relationship database for model organisms and important pathogens

BMC Systems Biology

Table 5 Table showing data overlap for same chosen pathways in difference source databases.

*M. musculus*	TCA cycle pathway	KEGG vs WikiPathways	KEGG vs MouseCyc	MouseCyc vs WikiPathways
Gene	Count	31 vs 30	31 vs 13	13 vs 30
	Overlap	24	13	11
	Jaccard Coefficient	0.65	0.42	0.34
Gene Pair	Count	100 vs 30	100 vs 24	24 vs 30
	Overlap	10	9	7
	Jaccard Coefficient	0.083	0.078	0.149
H. *sapiens*	Fatty Acid Biosynthesis	KEGG vs WikiPathways	KEGG vs HumanCyc	HumanCyc vs WikiPathways
Gene	Count	6 vs 22	6 vs 2	2 vs 22
	Overlap	3	2	1
	Jaccard Coefficient	0.12	0.33	0.04
Gene Pair	Count	12 vs 29	12 vs 2	2 vs 29
	Overlap	1	1	0
	Jaccard Coefficient	0.025	0.077	0.0
M . t *uberculosis* H37Rv	TCA cycle pathway	KEGG vs WikiPathways	KEGG vs MTBRvCyc	MTBRvCyc vs WikiPathways
Gene	Count	35 vs 34	35 vs 10	10 vs 34
	Overlap	34	10	10
	Jaccard Coefficient	0.97	0.29	0.29
Gene Pair	Count	107 vs 37	107 vs 19	19 vs 37
	Overlap	3	9	5
	Jaccard Coefficient	0.021	0.077	0.098

This table shows the calculation of gene/gene pair differences and overlap between the different source databases for the same chosen pathways.

ISSN: 1752-0509