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Table 8 Summary of number of pathways, average number of genes per pathway and average number of gene pairs per pathway before and after integration.

From: IntPath--an integrated pathway gene relationship database for model organisms and important pathogens

H. sapiens No. of Pathways BEFORE integration Average No. of genes/pathway Average No. of gene pairs/pathway
WikiPathways 135 pathways 46.3 166.2
HumanCyc 290 pathways 7.2 33.0
KEGG 237 pathways 72.4 171.3
H . sapiens No. of unique Pathways AFTER integration Average No. of genes/pathway Average No. of gene pairs/pathway
WikiPathways 100 pathways 42.7 157.4
HumanCyc 225 pathways 7.2 31.6
KEGG 201 pathways 72.6 165.3
Integrated Pathways 57 pathways 59.5 263.6
M . musculus No. of Pathways BEFORE integration Average No. of genes/pathway Average No. of gene pairs/pathway
WikiPathways 140 pathways 57.8 209.1
MouseCyc 323 pathways 8.0 61.4
KEGG 218 pathways 74.6 194.8
M . musculus No. of unique Pathways AFTER integration Average No. of genes/pathway Average No. of gene pairs/pathway
WikiPathways 97 pathways 56.8 242.8
MouseCyc 204 pathways 7.4 43.0
KEGG 172 pathways 77.9 187.3
Integrated Pathways 85 pathways 52.6 260.9
S . cerevisiae No. of Pathways BEFORE integration Average No. of genes/pathway Average No. of gene pairs/pathway
WikiPathways 125 pathways 11.8 0.5
YeastCyc 184 pathways 6.5 13.4
KEGG 98 pathways 35.2 34.7
S . cerevisiae No. of unique Pathways AFTER integration Average No. of genes/pathway Average No. of gene pairs/pathway
WikiPathways 45 pathways 15.1 0.2
YeastCyc 85 pathways 5.8 11.6
KEGG 80 pathways 38.0 35.0
Integrated Pathways 76 pathways 14.1 25.2
M. tuberculosis H37Rv No. of Pathways BEFORE integration Average No. of genes/pathway Average No. of gene pairs/pathway
WikiPathways 8 pathways 22.3 7.8
MTBRvCyc 234 pathways 5.7 18.9
KEGG 110 pathways 32.5 47.5
M . tuberculosis H37Rv No. of unique Pathways AFTER integration Average No. of genes/pathway Average No. of gene pairs/pathway
WikiPathways 0 pathways   
MTBRvCyc 171 pathways 5.9 21.0
KEGG 94 pathways 35.4 51.7
Integrated Pathways 35 pathways 12.3 25.4
  1. The table below shows the number of pathways from major pathway databases before and after integration.