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Table 6 Strong/weak motif class-wise average recognizability scores

From: MISCORE: a new scoring function for characterizing DNA regulatory motifs in promoter sequences

Strong/weak motif class-wise E{μ}over 10 runs

Motif class

apc (S t ) range

MAP

IC

R

R l

Weak (17/33 datasets)

apc ≤0.75

0.373

0.412

0.409

0.436

Strong (16/33 datasets)

apc >0.75

0.463

0.562

0.516

0.507

  1. Remark: recognizability scores obtained by the metrics are compared between strong and weak motifs. Results show that MISCORE noticeably outperforms MAP score and performs comparably to IC in recognizing weak motifs. However, the localized-MISCORE is likely to be more effective in recognizing weak motifs than IC and MAP score.
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BMC Systems Biology

ISSN: 1752-0509

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