Figure 6

Functional similarity (blue diamonds), depending on operon size, and a histogram showing the functional similarity (blue bars) of genes in the operons of genomes refactored under selective pressure on the expression of genes coding for enzymes (A and B, respectively), stress genes (C and D, respectively) and the whole genome (E and F, respectively). Notice that red squares and bars represent random evolutionary processes. Error bars show the minimum and maximum value of functional similarity of all operons with a given size (A, C and E) and represent standard deviation of operon frequency (B, D and F) for 10 evolutionary processes.