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Table 4 Comparison of methods on partial DREAM4 data

From: Joint estimation of causal effects from observational and intervention gene expression data

Criterion Dataset MCMC- Pinna IDA IDA
   Mallows   (opt) (pes)
  1 0.708 0.555 0.448 0.413
  2 0.525 0.637 0.610 0.641
AUROC 3 0.711 0.498 0.638 0.638
  4 0.748 0.682 0.554 0.483
  5 0.676 0.565 0.599 0.534
  1 0.344 0.346 0.142 0.133
  2 0.240 0.306 0.243 0.284
AUPRC 3 0.271 0.214 0.242 0.242
  4 0.322 0.494 0.162 0.158
  5 0.194 0.168 0.146 0.156
DREAM score overall 1.844 1.450 0.735 0.723
  1. Area under the ROC curve (AUROC), area under the precision-recall curve (AUPRC), and DREAM score for each of the five DREAM4 partial datasets, where only five of the single-gene knock-outs are included, for the MCMC-Mallows, Pinna et al., and IDA (optimistic and pessimistic) methods. Results for the Petri Nets method [17] are not provided as no software is publicly available to implement this approach. Evaluation scripts for the overall DREAM score were obtained from the DREAM4 evaluation page, located at http://wiki.c2b2.columbia.edu/dream/results/DREAM4.