Characterization of regulatory features of housekeeping and tissue-specific regulators within tissue regulatory networks

Table 1 Significant topological bias of TS/HK genes relative to trivial genes

P < 0.10. cc: cluster coefficient; Btwn: betweenness, Red five-pointed star: TS miRNAs; Green five-pointed star: TS TF; Green diamond: HK TF.
Red five-pointed star indicates that the relative centralities of TS miRNAs are significantly higher than those of trivial miRNAs in the corresponding tissue. Green five-pointed star indicates that the relative centralities of TS TFs are significantly higher than those of trivial TFs in the corresponding tissue; Green diamond indicates that the relative centralities of HK TFs are significantly higher than those of trivial TFs in the corresponding tissue. P < 0.10.

ISSN: 1752-0509