Table 3 Top 10 genes, TFs, and miRNAs with highest in-degree in lung cancer synergistic regulatory network

1

NTRK2

153

PMID: 21466358

2

ACVR2B

146

-

3

PLAG1

142

-

4

RAPH1

131

-

5

IGF1R

127

PMID: 22133293

6

CLCN5

123

-

7

FOXP1

123

PMID: 22904134

8

ACSL4

120

-

9

WHSC1

120

PMID: 22028615

10

ABHD2

120

-

1

E2F3

112

PMID: 16938365

2

ESR1

110

PMID: 18949413

3

PPARA

79

-

4

SMAD7

75

PMID: 21221812

5

ETS1

68

PMID: 17785952

6

MAFG

62

-

7

ETS2

56

PMID: 21922129

8

ARNT

54

PMID: 22645320

9

AHR

53

PMID: 21646808

10

FUBP1

51

PMID: 19258502

1

hsa-miR-129-5p

7

-

2

hsa-miR-19b

7

-

3

hsa-miR-219-5p

7

PMID: 16530703

4

hsa-miR-92a

7

-

5

hsa-miR-301b

6

-

6

hsa-miR-433

6

-

7

hsa-miR-557

6

-

8

hsa-miR-152

5

-

9

hsa-miR-16

5

PMID: 19549910

10

hsa-miR-329

5

-

11

hsa-miR-429

5

PMID: 19759262